Tecavir Indications/Uses

Entecavir monohydrate is indicated for the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and one evidence of continuous increase in serum aminotransferases (ALT or AST) or histologically active disease.
The following points should be considered when starting therapy with Entecavir monohydrate: Indication is based on the patient's histologic, virological, biochemical and serological responses adults on nucleoside-treatment-naive resistant to lamivudine with HBV infection chronic HBeAg-positive or HBeAg-negative and compensated liver disease; Virological, biochemical, serological and safety data are available from controlled studies in adult patients with chronic HBV infection and decompensated liver disease; Virological, biochemical, serological and safety data are available for a small number of adult patients with HIV/HBV coinfection who have previously received lamivudine therapy.