The information highlighted (if any) are the most recent updates for this brand.
Since Entecavir monohydrate is mainly excreted through the kidneys, giving Entecavir monohydrate along with drugs that reduce kidney function or compete for tubular secretions can increase serum concentrations of either Entecavir monohydrate or the drug given simultaneously. Co-administration Entecavir Monohydrate with lamivudine, adefovir dipivoxil, or tenofovir disoproxil fumarate did not produce significant drug interactions. The effect of giving Entecavir monohydrate concurrently with other drugs that are excreted via the kidneys or known to affect renal function has not been evaluated, and should be monitored closely against side effects in patients when Entecavir monohydrate is used together with the drug.