Sevoflurane Fahrenheit Dosage/Direction for Use

Vaporisers specifically calibrated for use with Sevoflurane should be used so that the concentration delivered can be accurately controlled. MAC (minimum alveolar concentration) values for Sevoflurane decrease with age and with the addition of nitrous oxide. The table as follows indicates average MAC values for different age groups. See table.


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Premedication: Premedication should be selected according to the need of the individual patient, and at the discretion of the anaesthetist. The use of anticholinergic drugs is a matter of choice.
Induction: Anesthesia can be induced in adults and children with Sevoflurane. Dosage should be individualized and titrated to the desired effect according to the patient's age and clinical status. A short acting barbiturate or other intravenous induction agent may be administered followed by inhalation of Sevoflurane. Induction with Sevoflurane may be achieved in oxygen or in combination with oxygen-nitrous oxide mixtures. In adults inspired concentrations of up to 5% Sevoflurane usually produce surgical anesthesia in less than 2 minutes.
In children, inspired concentrations of up to 7% Sevoflurane usually produce surgical anesthesia in less than 2 minutes.
Maintenance: Surgical levels of anesthesia may be sustained with concentration of 0.5-3% Sevoflurane with or without the concomitant use of nitrous oxide.
Elderly: As with other inhalation agents, lesser concentrations of Sevoflurane are normally required to maintain surgical anesthesia. See as previously mentioned for MAC values.
Emergence: Emergence times are generally short following Sevoflurane anaesthesia. Therefore, patients may require early post-operative pain relief.