Farpresin Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Vasopressin

Indications/Uses

Prevention & treatment of post-op abdominal distention, in abdominal roentgenography to dispel interfering gas shadows & in diabetes insipidus.

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Dosage/Direction for Use

IM Adult Abdominal distention Initially 5 U, may increase to 10 U at subsequent inj; given at 3 or 4 hr interval. Abdominal roentgenography 2 inj of 10 U, given 2 hr & 1½ hr respectively. Diabetes insipidus 5-10 U 2-3 times daily; may be given by inj or intranasally on cotton pledgets, by nasal spray or by dropper. IV Infusion Emergency management of acute GI bleeding Initially, 0.2-0.6 U/min, may increased to ≥0.6 U/min 30-60 min interval. After bleeding is controlled, continue effective dose 12-24 hr, dose should then be gradually tapered over the next 24-48 hr.

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Contraindications

Hypersensitivity or anaphylaxis.

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Special Precautions

Presence of epilepsy, migraine, asthma, heart failure, renal failure. Do not use in patients w/ vascular disease, especially disease of the coronary arteries. Small doses may precipitate anginal pain & the possibility of MI w/ larger doses. May produce water intoxication. Recognize the early signs of drowsiness, listlessness & headaches to prevent terminal coma & convulsions. Care should be taken to avoid extravascular tissue infiltration at the infusion site. May cause intense vasoconstriction that may lead to local necrosis & sloughing. Monitor ECG & fluid & electrolyte status. Conventional supportive measures (eg, blood transfusion, esophageal tamponade, paracentesis, nasogastric lavage) should accompany the use of vasopressin. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Anaphylaxis, cardiac arrest, circumolar pallor, arrythmias, decreased cardiac output, angina, MI, peripheral vasoconstriction, gangrene, abdominal cramps, nausea, vomiting, passage of gas, tremor, vertigo, pounding in head, bronchial constriction, sweating, urticaria, cutaneous gangrene.

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Drug Interactions

May potentiate the antidiuretic effect w/ carbamazepine, chlorpropamide, clofibrate, urea, fludrocortisone, TCA. May decrease the antidiuretic effect w/ demeclocycline, norepinephrine, lithium, heparin, alcohol. May produced a marked increase in sensitivity to the pressor effects w/ ganglionic blocking agents.

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Storage

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Description

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Action

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MIMS Class

Antidiuretics / Haemostatics

ATC Classification

H01BA01 - vasopressin (argipressin) ; Belongs to the class of vasopressin and analogues. Used in posterior pituitary lobe hormone preparations.

Regulatory Classification

Presentation/Packing

Form

Farpresin inj 20 u/mL

Packing/Price

1 mL x 5 × 1's

Farpresin

vasopressin

Manufacturer:

Fahrenheit