Cetrotide Dosage/Direction for Use

Cetrotide should only be prescribed by a specialist experienced in this field.
Administration: Cetrotide is for SC injection into the lower abdominal wall. The 1st administration of Cetrotide should be performed under the supervision of a physician and under conditions where treatment of possible pseudoallergic reactions is immediately available. The following injections may be self-administered as long as the patient is made aware of the signs and symptoms that may indicate hypersensitivity, the consequences of such a reaction and the need for immediate medical intervention.
The contents of 1 vial (cetrorelix 0.25 mg) are to be administered once daily, at 24 hrs intervals, either in the morning or in the evening. Following the 1st administration, it is advised that the patient be kept under medical supervision for 30 min to ensure there is no allergic/pseudoallergic reaction to the injection. Facilities for the treatment of such reactions should be immediately available.
Administration in the Morning: Treatment with Cetrotide should commence on day 5 or 6 of ovarian stimulation (approximately 96-120 hrs after start of ovarian stimulation) with urinary or recombinant gonadotropins and is to be continued throughout the gonadotropin treatment period including the day of ovulation induction.
Administration in the Evening: Treatment with Cetrotide should commence on day 5 of ovarian stimulation (approximately 96-108 hrs after start of ovarian stimulation) with urinary or recombinant gonadotropins and is to be continued throughout the gonadotropin treatment period until the evening prior to the day of ovulation induction.
Missed a Dose: If you missed to administer Cetrotide on one day, please contact your doctor immediately and ask for advice. Ideally Cetrotide should be administered at 24 hrs intervals. But if you missed to administer Cetrotide at the right time it is no problem to administer this dose at a different time on the same day.