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Effect of Other Drugs on TRODELVY: UGT1A1 Inhibitors: Concomitant administration of TRODELVY with inhibitors of UGT1A1 may increase the incidence of adverse reactions due to potential increase in systemic exposure to SN-38 [see Increased Risk of Adverse Reactions in Patients with Reduced UGT1A1 Activity under Precautions; and Pharmacology: Pharmacokinetics and Pharmacogenomics under Actions]. Avoid administering UGT1A1 inhibitors with TRODELVY.
UGT1A1 Inducers: Exposure to SN-38 may be reduced in patients concomitantly receiving UGT1A1 enzyme inducers [see Increased Risk of Adverse Reactions in Patients with Reduced UGT1A1 Activity under Precautions; and Pharmacology: Pharmacokinetics and Pharmacogenomics under Actions]. Avoid administering UGT1A1 inducers with TRODELVY.
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