Tanakan

For one tablet: Active compound: Standardized Ginkgo biloba Extract (EGb 761) containing 24% of Ginkgo heterosides and 6% of Ginkgolides-bilobalide 40 mg.
Excipients/Inactive Ingredients: Lactose monohydrate, microcrystalline cellulose, maize starch, anhydrous colloidal silica, talc, magnesium stearate, hypromellose, Macrogol 400, Macrogol 6000, titanium dioxide, red iron oxide.

Pharmacology: Vasoregulating action on vascular system; Rheological effects, mainly anti-PAF (Platelet Activating Factor) and anti-sludge properties; Protective effect on cellular metabolism; Improvement in neurotransmission; Free radical scavenging and anti-ischaemic effects.
Pharmacokinetics: The active ingredient is standardized Ginkgo biloba extract titrated at 24% with heterosides of Ginkgo and 6% of di and sesquiterpene (ginkgolides A, B and C bilobalide).
In man, only the pharmacokinetic parameters of the terpenic fraction have been highlighted.
The ginkgolides A and B and the bilobalide have an oral bioavailability of 80 to 90%. Maximum concentration is reached in 1 to 2 hours; the elimination half-lives last for around 4 hours (bilobalide, ginkgolide A) to 10 hours (ginkgolide B). These substances are not broken down in the body and they are principally eliminated in the urine, and a small quantity excreted in the stools.

This drug is recommended for: the treatment of minor neurologic disorders related to the age, symptomatic treatment of arteritis of the lower limbs (leg arteries disease involving painful cramps during walking), ocular disorders and other disorders (hearing or vertigo) of circulatory origin, Raynaud's disease.

1 dose = 1 tablet = 40 mg of pure extract.
Usual dosage: 3 tablets per day (in divided doses) at mealtimes. Tablets should be taken with a half-glass of water, during meals.

Not applicable.

Since this medicinal product contains lactose, it is contraindicated in subjects presenting with congenital galactosemia, glucose or galactose malabsorption syndrome or with lactase deficiency.

This medicine is contraindicated in the following circumstance: Hypersensitivity to one of the ingredients of the tablet.
This medicine is mainly used for the elderly, for whom the risk of pregnancy is non-existent.
In the absence of relevant clinical data, the use of this product is not recommended during pregnancy or breastfeeding.

Adverse effects have been rarely reported: digestive disorders, skin disorder, headaches.

To be stored at cool and dry place, below 25°C.

Peripheral Vasodilators & Cerebral Activators

N06DX02 - Ginkgo folium ; Belongs to the class of other anti-dementia drugs.

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