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A limited number of accidental overdoses of Sandostatin LAR have been reported. The doses ranged from 100-163 mg/month of Sandostatin LAR. The only adverse event reported was hot flushes.
Cancer patients receiving doses of Sandostatin LAR up to 60 mg/month and up to 90 mg/2 weeks have been reported. These doses were in general well tolerated; however, the following adverse events have been reported: Frequent urination, fatigue, depression, anxiety, and lack of concentration.
The management of overdosage is symptomatic.
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