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Each vial contains octreotide microspheres free peptide 10, 20 or 30 mg nominally 4.15% of fill weight equivalent to 4.65% of octreotide acetate. It also contains poly (DL-lactide-co-glycolide) 78.35% of nominal fill weight; sterile mannitol 17% of nominal fill weight.
Without Vial Adapter/Safety Needle: One pre-filled syringe (solvent for parenteral use) containing sodium carboxymethylcellulose 12.5 mg, mannitol 15 mg and water for injection 2.5 mL plus 2 needles [40 mm (1.5 inch), 20 gauge].
With Vial Adapter and Safety Needle: One pre-filled syringe (solvent for parenteral use) containing sodium carbosymethylcellulose 14 mg, mannitol 12 mg, poloxamer 188 4 mg and water for injections.
Sandostatin LAR is a long-acting depot injection form of octreotide. Microspheres to be suspended in a vehicle immediately prior to IM injection.
Sandostatin LAR suspension contains <1 mmol (23 mg) of sodium per dose ie, essentially sodium-free.
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