Orkedia Adverse Reactions

Since the following adverse reactions may occur, patients should be carefully monitored. If any abnormalities occur, appropriate measures including treatment discontinuation should be taken.
Clinically Significant Adverse Reactions: Hypocalcemia (16.2%): If symptoms derived from hypocalcemia (QT prolongation, numbness, muscle spasms, discomfort, arrhythmia, decreased blood pressure, convulsions, etc.) occur, the physician must check serum calcium levels and consider the need to administer calcium and/or vitamin D preparations (see Precautions Concerning Dosage and Administration: Secondary hyperparathyroidism in patients on maintenance dialysis and Hypercalcaemia in patients with parathyroid carcinoma and hypercalcaemia in patients with primary hyperparathyroidism who are unable to undergo parathyroidectomy or patients with recurrent primary hyperparathyroidism after parathyroidectomy under Precautions; Important Precautions under Precautions; Precautions Concerning Patients with Specific Backgrounds: Patients with Complication or History of Diseases, etc.: Patients with hypocalcemia under Precautions; QT prolongation (0.6%) as follows; and Measures under Overdosage).
QT prolongation (0.6%): see Hypocalcemia (16.2%) as previously mentioned.
Other Adverse Reactions: See Table 9.

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