Nimill Contraindications

Established individual hypersensitivity to nimesulide, to acetylsalicylic acid or to other non-steroidal anti-inflammatory drugs, gastrointestinal hemorrhage in progress or active gastro-duodenal ulcer, asthma, severe renal impairment, moderate of severe hepatic impairment. Nimesulide must not be administered to patients with a history of presence of hepatic disease. NIMILL should not be given to patients who have demonstrated allergic-type reaction to sulfonamides.
The third trimester of pregnancy, because of risks of premature closure of the ductus arteriosus, and prolonged parturition.
Contraindicated in children under 12 years of age.
NIMILL is also contraindicated in patients with severe heart failure and for the treatment of peri-operative pain in the setting of coronary artery bypass graft surgery.
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy; active, or history of recurrent peptic ulcer/haemorrhage.