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Hypersensitivity to local anaesthetics of the amide type or to any of the excipients.
Hypersensitivity to sodium metabisulphite in solutions containing adrenaline.
Use in connection with anaesthesia in areas of the body supplied by end arteries (e.g. penile block, Oberst block) as it may cause ischemic tissue necrosis or otherwise having a compromised blood supply such as digits, nose, external ear, penis, etc., or in spinal anaesthesia because of the adrenaline content; plain solutions must be used for this purpose.
Intravenous regional anaesthesia (Bier's-block) and for injection into inflamed or infected areas.
Use in paracervical block in obstetrics.
Patients with thyrotoxicosis or severe heart disease, particularly when tachycardia is present.
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