MACMIROR Complex 500 is the combination of Nifuratel and Nystatin. Nifuratel is a synthetic chemotherapeutic agent, which has a considerable and effective trichomonacidal, antibacterial and mycostatic activity: its multiple effects allows the treatment of vaginitis of mixed etiology and the prevention, contrarily to other products, of mycoses deriving from the specific treatment of trichomoniasis.
Nystatin is a well-known fungicidal antibiotic, particularly active against mycetes of Candida type.
The Nifuratel-Nystatin combination enables to reach a "total fungicidal effect" and to develop a multiple therapy of vaginitis which ensures elimination of the pathogenic agents responsible for the infections (Candida a., Trichomonas v. and bacteria) and restores the physiologic conditions of the vaginal flora. This with the aim of preventing relapses following an apparent recovery from the primary infections.