Leqembi Caution For Usage

Dilution Instructions: Prior to administration, LEQEMBI must be diluted in 250 mL of 0.9% Sodium Chloride Injection, USP.
Use aseptic technique when preparing the LEQEMBI diluted solution for intravenous infusion.
Calculate the dose (mg), the total volume (mL) of LEQEMBI solution required, and the number of vials needed based on the patient's actual body weight and the recommended dose of 10 mg/kg. Each vial contains a LEQEMBI concentration of 100 mg/mL.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Check that the LEQEMBI solution is clear to opalescent and colorless to pale yellow. Do not use if opaque particles, discoloration, or other foreign particles are present.
Remove the flip-off cap from the vial. Insert the sterile syringe needle into the vial through the center of the rubber stopper.
Withdraw the required volume of LEQEMBI from the vial(s) and add to an infusion bag containing 250 mL of 0.9% Sodium Chloride Injection, USP.
Each vial is for one-time use only. Discard any unused portion.
Gently invert the infusion bag containing the LEQEMBI diluted solution to mix completely. Do not shake.
After dilution, immediate use is recommended [see Description]. If not administered immediately, store LEQEMBI refrigerated at 2°C to 8°C (36°F to 46°F) for up to 4 hours, or at room temperature up to 25°C (77°F) for up to 4 hours. Do not freeze.