Leqembi Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Caution For Usage Storage Patient Counseling Information MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Lecanemab

Indications/Uses

Alzheimer's disease. Initiated in patients w/ mild cognitive impairment or mild dementia stage of disease.

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Dosage/Direction for Use

IV infusion 10 mg/kg diluted then administered over approx 1 hr, once every 2 wk.

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Contraindications

Hypersensitivity.

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Special Precautions

Promptly discontinue infusion upon 1st observation of hypersensitivity reactions. Risk of amyloid related imaging abnormalities (ARIA), characterized as ARIA w/ edema (ARIA-E) & ARIA w/ hemosiderin deposition (ARIA-H). Perform ApoE ε4 status testing prior to treatment initiation to inform the risk of developing ARIA. Risk of intracerebral hemorrhage; increased in patients w/ risk factors or concomitantly taking anticoagulants or a thrombolytic agent. Risk of infusion-related reactions. Discontinue or reduce infusion rate in case of an infusion-related reaction. Consider prophylactic treatment w/ antihistamines, acetaminophen, NSAIDS or corticosteroids prior to future infusions. No adequate data on use in pregnant women & lactation. Safety & effectiveness in ped patients have not been established.

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Use In Pregnancy & Lactation

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Adverse Reactions

Infusion-related reactions, headache, ARIA-E, ARIA-H, superficial siderosis of CNS, cough, diarrhea, rash, nausea/vomiting.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Leqembi detailed prescribing information

Storage

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Description

View Leqembi description for details of the chemical structure and excipients (inactive components).

Action

View Leqembi mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Neurodegenerative Disease Drugs

ATC Classification

N06DX04 - lecanemab ; Belongs to the class of other anti-dementia drugs.

Regulatory Classification

P₁S₁S₃

Patient Counseling Information

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Presentation/Packing

Form

Leqembi conc for soln for infusion 200 mg/2 mL

Packing/Price

1's

Leqembi

lecanemab

Manufacturer:

Eisai

Distributor:

The Glory Medicina

DKSH