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Pregnancy: No controlled studies with calcifediol in pregnant women have been performed.
Studies performed in animals have shown toxicity for reproduction (see Pharmacology: Toxicology: Preclinical safety data under Actions).
Do not use calcifediol 0.266 mg soft capsules during pregnancy.
Breast-feeding: Calcifediol is excreted into breast milk.
The risk in newborns/infants cannot be excluded. Maternal ingestion of high doses of calcifediol can produce high levels of calcitriol in milk and cause hypercalcemia in infants.
This medicine should not be used during breast-feeding.
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