Exib Dosage/Direction for Use

Recommended dose: Osteoarthritis: 30 mg or 60 mg once daily (maximum 60 mg once daily).
Rheumatoid arthritis: 60 mg or 90 mg once daily (maximum 90 mg once daily).
Ankylosing spondylitis: 60 mg or 90 mg once daily (maximum 90 mg once daily).
Acute gouty arthritis: 120 mg once daily (limited to a maximum of 8 days treatment).
Postoperative dental surgery pain: 90 mg once daily (limited to a maximum of 3 days treatment).
Acute pain conditions: Etoricoxib should be used only for acute symptomatic period.
Elderly patients: No dosage adjustment is necessary.
Pediatric patients: Etoricoxib is contraindicated in children and adolescent under 16 years of age.
Patients with hepatic impairment: Mild hepatic dysfunction (Child-Pugh score 5-6): the maximum oral dose of etoricoxib, regardless of indications is 60 mg once daily.
Moderate hepatic dysfunction (Child-Pugh score 7-9): the maximum oral dose of etoricoxib, regardless of indications is 30 mg once daily.
There is no data in patients with severe hepatic dysfunction (Child-Pugh score >10), etoricoxib should not be given to patients with severe hepatic dysfunction.
Patients with renal impairment: Creatinine clearance ≥30 mL/min: no dosage adjustment is necessary.
Creatinine clearance <30 mL/min: treatment with etoricoxib is contraindicated.
Remarks: For dose 30 mg and 60 mg, use the other preparation.
*Etoricoxib should be used at the lowest effective dose for shortest possible time.
Mode of Administration: Etoricoxib is administered orally. It may be taken with or without food.