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Each vial contains 120 mg denosumab in 1.7 mL solution (70 mg/mL).
Excipients/Inactive Ingredients: Sorbitol, Glacial acetic acid*, Polysorbate 20, Sodium hydroxide, Water for Injection.
* Acetate buffer is formed by mixing acetic acid with sodium hydroxide.
Sterile, preservative-free, clear, colorless to slightly yellow solution, pH 5.2.
Before administration, XGEVA should be inspected for particulate matter and discoloration. The solution should not be used if cloudy or discolored.
The solution may contain trace amounts of translucent to white proteinaceous particles.
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