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Known allergy or hypersensitivity to Progesterone or to any of the excipients. The capsules contain sunflower oil and should never be used by patients allergic to sunflower seed. Undiagnosed vaginal bleeding. Mammary or genital tract carcinoma. Thrombophlebitis. Thromboembolic disorders. Cerebral haemorrhage. Porphyria.
Increased risk of venous thromboembolism is documented with the use of oral contraceptive pill and oral HRT related to the estrogen component. No study has evaluated the effect of the progestin component alone in HRT.
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