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Tacrograf is indicated for: prophylaxis of organ rejection in patients receiving allogeneic liver or kidney transplants. It is recommended that Tacrograf be used concomitantly with adrenal corticosteroids. In kidney transplant recipients, it is recommended that Tacrograf be used in conjunction with azathioprine or mycophenolate mofetil (MMF). The safety and efficacy of the use of Tacrograf with sirolimus has not been established.
Lupus nephritis (in a case where the effect of steroids is insufficient or administration of steroids is difficult because of their adverse reactions). For lupus nephritis, the efficacy and safety of this product for patients in an acute phase with high disease activity has not been established.
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