Posology: The recommended dosage of JESELHY is 160 mg of pimitespib administered orally once daily on an empty stomach for 5 consecutive days, followed by 2 days off, and repeated. When administered in the fed state, the C
max and AUC of JESELHY increase. To avoid food effects, JESELHY should not be taken between 1 hour before and 2 hours after a meal.
Dose adjustments for toxicity: If an adverse reaction occurs, treatment with JESELHY should be interrupted or the dose reduced according to symptoms and severity, taking into account the following criteria. (See Tables 3 and 4.)
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Click on icon to see table/diagram/image
Posology adjustments for special populations: None.
Method of administration: JESELHY is for oral administration.