Ergotamine tartrate, caffeine.
Each tablet contains Ergotamine Tartrate 1 mg, Caffeine 100 mg.
HOFERGOT is used in the treatment of migraine attacks and vascular headache.
Adults and children over 12 years of age: 1-2 tablets at the first warning of an attack. If necessary, another tablet may be taken at half-hourly intervals but should not exceed 6 tablets per day and 10 tablets in one week.
Children under 12 years of age: as prescribed by the physician.
It is contraindicated in normal headache, patients with vascular diseases or suspected of hypertension, hepatic and renal diseases, pregnant women or nursing mothers, gastritis, malnutrition, sepsis, or those who are hypersensitive to ergot alkaloids.
If symptoms of numbness, chill, weakness in the legs and arms or muscle pains, abdominal pain, nausea, vomiting, diarrhea and headache occur, discontinue the drug and consult the physician.
It is contraindicated in pregnant women or nursing mothers.
Nausea, vomiting, vertigo.
Transient tachycardia or bradycardia, Precordial distress and pain.
Muscle pain, Paresthesias, Weakness.
Concomitant use of Hofergot with cytochrome P450 inhibitors such as macrolide antibiotics (e.g. erythromycin, clarithromycin, troleandomycin, spiramycin, josamycin), azole antimycotics (e.g. ketoconazole, itraconazole), protease inhibitors (e.g. ritonavir, indinavir) or cimetidine must be avoided, as these increase plasma ergotamine levels, possible resulting in peripheral vasoconstriction. Concomitant use of vasoconstrictor agents such as ergotamine, selective vascular 5HT1 receptor agonists or nicotine (e.g. smoking) may increase the risk of vasoconstriction. Although the combination of beta blockers and Hofergot is generally well tolerated, caution is required in susceptible patients.
N02CA52 - ergotamine, combinations excl. psycholeptics ; Belongs to the class of ergot alkaloids preparations. Used to relieve migraine.
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