Discontinue use immediately if adverse skin reaction occurs. Not to be used in patients who develop asthma, hives or swelling & irritation inside the nose after taking aspirin or any other NSAIDs. Not to be applied on broken skin, wounds, infected skin or soft tissues; skin affected by exudative dermatitis or eczema. Avoid use in patients w/ active peptic ulcer or GI bleeding; liver or kidney disease or those w/ liver or renal impairment. Increased risk of platelet, CV & circulatory system abnormalities w/ prolonged use. May mask signs of skin infection. Patients w/ bronchial asthma. Adequately monitor patients while on treatment. Use concomitantly w/ antibiotics or antifungals, as appropriate, when used on inflamed & infected areas. Avoid use during pregnancy, especially in the last trimester, or in patients who may be pregnant; breastfeeding. Ductus arteriosus constriction in infants whose mothers received other transdermal non-steroidal anti-inflammatory analgesics during 3rd trimester of pregnancy. Not to be used in childn <15 yr. Elderly.