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Potential interactions between Elidel 1% cream and other drugs have not been systematically evaluated. Based on its minimal extent of absorption, interactions of Elidel 1% cream with systemically administered drugs are unlikely to occur (see Pharmacology: Pharmacokinetics under Actions).
A study that included 79 infants treated for up to 2 years showed that treatment with Elidel 1% cream did not interfere with the protective immune response to childhood vaccinations. Application of Elidel 1% cream to vaccination sites, as long as local reactions persist, was not studied and is therefore not recommended.
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