Dermazin Dosage/Direction for Use

An appropriate treatment regimen is promptly instituted after evaluating the depth of the burn wound. The burn wound is then cleansed and debrided and covered with Dermazin cream to a thickness of 2 to 4 mm. The cream is applied to sterile gauze which is placed over the burn. The cream may be also applied using a sterile spatula or a sterile gloved hand. The cream is usually applied to the burn area once daily, for more severe burns application of the cream can be repeated; however, the cream should be reapplied at least once in 24 hours. Prior to each cream reapplication, the burn wound must be cleaned off any previous cream remnants and wound exudates, which are copious after Dermazin application resembling pus in colour but actually aseptic, with water or an antiseptic agent. Dressings can be applied over the cream although it is not necessary.
Dermazin cream in jars is intended for repeated application in one patient only. The cream does not cause pain on application. It leaves no stains on clothes and bed linen.
Renal/hepatic impairment: Precaution is needed when Dermazin is used in patients with impaired hepatic and renal function sulfadiazine can be absorbed in significant quantities following prolonged treatment of extensive burns, and measurement of sulfadiazine levels may be indicated.
Paediatric population: This cream is contraindicated in premature infants and in newborn infants during the first 2 months of life because of the possible occurrence of kernicterus after sulphonamide therapy.
The recommended dosage of the cream for infants older than 2 months and children does not differentiate between pediatric and adult population. The method of application in children is the same as in adults.