Capiibine Adverse Reactions

See Tables 4a and 4b.

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Frequency not defined: Cardiovascular: Angina pectoris, cardiac arrest, cardiac arrhythmia, cardiac failure, cardiomyopathy, ECG changes, ischemic heart disease, myocardial infarction.
Gastrointestinal: necrotizing enterocolitis.
Less than 1%, postmarketing, and/or case reports: Cardiovascular: Cerebrovascular accident, hypertension, hypotension, myocarditis, phlebitis (venous), pulmonary embolism, syncope, tachycardia.
Central Nervous system: Confusion, leukoencephalopathy (toxic), loss of consciousness.
Dermatologic: Cutaneous lupus erythematosus, diaphoresis, ecchymoses, Stevens - Johnson syndrome; toxic epidermal necrolysis.
Endocrine & metabolic: Cachexia, hypertriglyceridemia.
Gastrointestinal: Esophagitis, gastric ulcer, gastroenteritis, gastrointestinal perforation.
Genitourinary: Nocturia.
Hematologic & Oncologic: Bone marrow depression, leukopenia, pancytopenia.
Hepatic: Ascitis, blood coagulation disorder, cholestatic hepatitis, hepatic failure, hepatic fibrosis, hepatitis, jaundice.
Hypersensitivity: Hypersensitivity.
Infection: Fungal infection, sepsis.
Miscellaneous: Fibrosis, radiation recall phenomenon.
Neuromuscular & skeletal: Arthritis, ostealgia.
Ophthalmic: Keratitis, lacrimal stenosis, photopobia.
Renal: Acute renal failure, renal insufficiency.
Respiratory: Asthma, bronchitis, bronchopneumonia, bronchospasm, pneumonia, respiratory distress.