Appropriate medical treatment & supervision should be available in case of rare anaphylactic event following vaccination. Do not administer as IV, intradermal or SC. Syncope can occur; place procedures to avoid injury from fainting. Postpone vaccination in individuals w/ acute severe febrile illness. Individuals w/ thrombocytopenia or any coagulation disorder or those receiving anticoagulant therapy. May diminish immune response to Trumenba in immunocompromised persons including those receiving immunosuppressant therapy. Increased risk for invasive disease especially in persons w/ certain complement deficiencies & those receiving treatment that inhibits terminal complement activation (eg, eculizumab). May not protect all vaccine recipients. Separate inj sites & use different syringes if >1 vaccine is administered at the same time. Pregnancy & lactation. Childn <10 yr. Elderly >65 yr.
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