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TRAMAPAN is contraindicated: in all children younger than 12 years of age.
In post-operative management in children younger than 18 years of age following tonsillectomy and/or adenoidectomy.
In patients who have previously demonstrated hypersensitivity to tramadol, paracetamol or any other components (see Description) of this product or opioids.
In cases of acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs.
In patients using monoamine oxidase inhibitors (MAOI) concurrently or within the last 14 days (see Interactions).
In patients with significant respiratory depression (see Precautions).
