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Thyrozol should not be used in patients with: hypersensitivity to thiamazole, other thionamide derivatives or any of the excipients; moderate to severe blood count disturbances (granulocytopenia); preexisting cholestasis not caused by hyperthyroidism; previous damage to bone marrow after treatment with carbimazole or thiamazole; a history of acute pancreatitis after administration of thiamazole or its prodrug carbimazole.
Combination therapy with thiamazole and thyroid hormones is contraindicated during pregnancy (see Use in Pregnancy & Lactation).
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