Saizen Contraindications

Saizen should not be used in children in whom epiphyseal fusion occurred.
Saizen is contraindicated in patients known to be hypersensitive to Somatropin and any of the excipients in the solution for injection.
Saizen is contraindicated in patients with active neoplasia. Any anti-tumor therapy must be completed prior to starting treatment with Somatropin.
Saizen should not be used in cases with evidence of any progression or recurrence of an underlying intra-cranial lesion.
Patients with acute critical illness suffering complications following open heart surgery, abdominal surgery, multiple accidental trauma, acute respiratory failure or similar conditions should not be treated with Somatropin. (Regarding patients undergoing Somatropin therapy and becoming critically ill, see "Precautions".)
Saizen is contraindicated in patients with proliferative or pre-proliferative diabetic retinopathy.
Saizen is contraindicated in pregnancy and lactation.
In children with chronic renal disease, treatment with somatropin should be discontinued at renal transplantation.