Posatif Dosage/Direction for Use

Important Administration Instructions: Non-Interchangeability between Posaconazole Delayed Release Tablets and Posaconazole Oral Suspension: The prescriber should follow the specific dosing instructions for each formulation. The tablet and oral suspension are not to be used interchangeably due to the differences in the dosing of each formulation.
Posatif Posaconazole gastro-resistant tablets: Tablets should not be administered together with alcohol.
Swallow tablets whole. Do not divide, crush, or chew.
Tablets may be taken without regard to food intake. (See Table 3.)

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Use in renal impairment: No dose adjustment is required for renal dysfunction and posaconazole is not significantly renally eliminated, an effect of severe renal insufficiency on the pharmacokinetics of posaconazole is not expected and no dose adjustment is recommended.
Use in hepatic impairment: There are limited pharmacokinetic data in patients with hepatic insufficiency; therefore, no recommendation for dose adjustment can be made. In the small number of subjects studied who had hepatic insufficiency, there was an increase in half-life with a decrease in hepatic function.
Use in children: Safety and efficacy in children below the age of 13 years have not been established.
Mode/Route of Administration: Oral route of administration.