Newborn: For prophylaxis, 100,000 units once daily may be given by dropper directly into the mouth.
Infants: Usual prophylactic and therapeutic dosage is 100,000 units 4 times daily, dropped into the side of the mouth and swallowed. Dosage may be increased if necessary.
Children and adults: Usual therapeutic dose is 100,000 units 4 times daily dropped into the mouth and held or swished throughout the mouth for as long as possible, then gargled and swallowed.
Missed Dose: If the patient missed a dose, take the missed dose as soon as possible, unless it is almost time for the next dose. Skip the missed dose if it is almost time for the next regular dose. Do not take two doses at the same time.