Pantin 20/40 Dosage/Direction for Use

Mild reflux disease and associated symptoms (e.g. heartburn, acid regurgitation, pain on swallowing): The recommended oral dosage is one gastro-resistant tablet Pantoprazole Gastro-Resistant Tablets 20 mg per day. Symptom relief is generally accomplished within 2-4 weeks, and a 4-week treatment period is usually required for healing of associated oesophagitis. If this is not sufficient, healing will normally be achieved within a further 4 weeks.
Long-term management and prevention of relapse in reflux oesophagitis: For long-term management, a maintenance dose of one gastroresistant tablet Pantoprazole Gastro-Resistant Tablets 20 mg per day is recommended, increasing to 40 mg pantoprazole per day if a relapse occurs.
Pantoprazole Gastro-Resistant Tablets 40 mg is available for this case. After healing of the relapse the dosage can be reduced again to 20 mg pantoprazole.
Treatment of Moderate and severe reflux oesophagitis: For the treatment of reflux esophagitis one tablet of Pantoprazole Gastro-Resistant Tablets 40 mg per day. In individual cases the dose may be doubled (increase to 2 tablets Pantoprazole Gastro-Resistant Tablets 40 mg daily) especially when there has been no response to other treatment.
Special Populations: Hepatic Impairment: A daily dose of pantoprazole 20 mg should not be exceeded in patients with severe liver impairment.
In patients with severe liver impairment the dose has to be reduced to 1 tablet (40 mg pantoprazole) every other day. Furthermore, in these patients the liver enzymes should be monitored during Pantoprazole Gastro-Resistant Tablets 40 mg therapy. In the case of a rise of the liver enzymes, Pantoprazole Gastro-Resistant Tablets 40 mg should be discontinued.
Renal Impairment: No dose adjustment is necessary in elderly patients of in those with impaired renal function.
Elderly: The daily dose of 40 mg pantoprazole should not be exceeded in elderly patients or in patients with impaired kidney function.
General instructions: Pantoprazole Gastro-Resistant Tablets tablets should not be chewed or crushed, and should be swallowed whole with water 1 hour before a meal.
A 4-week period is usually required for the treatment of reflux esophagitis. If this is not sufficient, healing will usually be achieved within a further 4 weeks.