M-M-R II Description

M-M-R II (Measles, Mumps, and Rubella Virus Vaccine Live) is a live virus vaccine for vaccination against measles, mumps, and rubella.
M-M-R II is a sterile lyophilized preparation of (1) a more attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture; (2) the Jeryl Lynn (B level) strain of mumps virus propagated in chick embryo cell culture; and (3) the Wistar RA 27/3 strain of live attenuated rubella virus propagated in WI-38 human diploid lung fibroblasts.
The reconstituted vaccine is for intramuscular or subcutaneous administration. When reconstituted as directed, the dose for injection is approximately 0.5 mL and contains not less than 1,000 CCID₅₀ (50% cell culture infectious dose) of measles virus; 12,500 CCID₅₀ of mumps virus; and 1,000 CCID₅₀ of rubella virus.
Each approximately 0.5 mL dose of the vaccine contains (approximately): sorbitol (14.5 mg), sodium phosphate, sucrose (1.9 mg), hydrolyzed gelatin (14.5 mg), recombinant human albumin (≤0.3 mg), fetal bovine serum (<1 ppm), other buffer and media ingredients and approximately 25 μg of neomycin. The product contains no preservative.