Appropriate medical treatment must be available & provide close supervision if rare anaphylactic reaction occurs following vaccination. Do not administer intravascularly. Individuals w/ thrombocytopenia or bleeding disorders. Immunosuppressive treatment or immunodeficiency condition may induce reduced immune response to vaccine; wait until the end of treatment before vaccinating. Recommended for individuals in whom oral vaccine is contraindicated & as booster for those previously vaccinated w/ oral vaccine. Syncope may occur; put procedures in place to prevent injury due to fainting. Contains phenylalanine which may be dangerous for patients w/ phenylketonuria; ethanol 2 mg/dose & Na 23 mg/dose. May be prescribed during pregnancy in high-risk situations. Consider potential risk of apnoea & need for resp monitoring for 48-72 hr when administering primary immunisation series to very premature infants (≤28 wk of gestation) & particularly for those w/ history of resp immaturity.