Sign Out
Pharmacology: Pharmacodynamics: Clobetasol Propionate is a topically active fluorinated
corticosteroid (cream) which has anti-inflammatory, anti-pruritic and vasoconstrictive actions.
Pharmacokinetics: Clobetasol propionate has anti-inflammatory, anti-pruritic, and vasoconstrictive actions. When administered topically, particularly under occlusive dressings or when the skin is broken, sufficient corticosteroid may be absorbed to give systemic effects. Corticosteroids are extensively bound to plasma proteins. Only unbound corticosteroids have pharmacological effects or are metabolized. They are metabolized mainly in the liver, also in the kidneys, and are excreted in the urine.
Continue with Google