Beta-Nicardia Special Precautions

Cardiac: Care is needed in patients with conduction defects or poor cardiac reserve. At start of therapy, patients may experience angina attacks or increase in frequency, duration and severity of angina attacks. There have been isolated reports of myocardial infarction.
Care is needed in co-administration with class I antiarrhythmic agents and with anaesthetics.
Avoid use in patients with reversible obstructive airways disease unless there are compelling clinical reasons. In such case, use with caution.
Caution when shifting patients from clonidine.
Withdrawal of Beta-Nicardia should be gradual in patients with ischemic heart disease.
Diabetes: Patients may require adjustment of their diabetic therapy. The tachycardia of hypoglycemia may be modified.
Hepatic or Renal Impairment: Beta-Nicardia is considered inappropriate in patients with marked renal impairment (ie, creatinine clearance <15 mL/min/1.73 m², serum creatinine >600 micromoles/L). Care is needed in patients with marked hepatic impairment.
Use in children: Beta-Nicardia is not indicated for children.