Bentrio Mechanism of Action

The nasal cavities are lined with mucosa which serves as the body's first line of defence against inhaled particles such as pollen, house dust mites, animal dander or viruses. The nasal mucosa acts as a protective barrier against these particles; it secrets mucus which traps particles for clearance via the throat. Its protective function may be compromised by nasal dryness or irritation (e.g. due to low air humidity, certain nasal sprays) or mucosal damage. Also, it may be overwhelmed by the quantity or infectiousness of inhaled particles. Bentrio protects the nasal mucosa in three ways: forms a thin protective layer on the nasal mucosa; binds inhaled particles through electrostatic effects; humidifies the mucosa and thus aids its functionality.
The gel formulation of Bentrio has been designed for extended residence time within the nose. Upon shaking of the spray bottle, it turns liquid which allows for spraying into the nose. After contact with the nasal mucosa, the formulation returns to its gel state and creates the protective barrier.
Bentrio is cleared from the nasal cavities over time into the throat and eliminated via the digestive tract.