The most serious adverse reactions occasionally reported are leucopenia, jaundice, hypersensitivity and paradoxical reactions (such as hyperexcited states, anxiety, excitement, hallucinations, increased muscle spasticity, insomnia, rage, as well as sleep disturbances and stimulation - should these occur, the drug should be discontinued.
Minor changes in EEG patterns have been observed in patients on Diazepam therapy. These changes consist of low to moderate voltage fast activity, 20 to 30 cycles per second and are of no known significance.
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