In the treatment of patients with acute ischemic cerebral vascular disease. Citicoline accelerates recovery of consciousness and motor deficit, achieves a better final outcome, and facilitates rehabilitation of these patients. The other major indication of Citicoline is for the treatment of senile cognitive impairment, either secondary to degenerative diseases (e.g Alzheimer disease) or to chronic cerebral vascular disease. In patient with chronic cerebral ischemia, Citicoline improves scores in cognitive rating scales, while in patients with senile dementia of the Alzheimer type it stops the course of the disease, and neuroendocrine, neuroimmunomodulatory, and neurophysiological benefits have been reported. Citicoline has also been shown to be effective in Parkinson disease, drug addictions, and alcoholism, as well as in amblyopia and glaucoma.
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