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Caution should be taken when giving ciprofloxacin to epileptic patients and to those with history of CNS disorders, myasthenia gravis and glucose-6-phosphate dehydrogenase deficiency. Ciprofloxacin may exacerbate or unmask symptoms of myasthenia gravis. If tendon pain, inflammation or rupture occurs, treatment with ciprofloxacin should be discontinued.
Ciprofloxacin is contraindicated in children, adolescents, pregnant women and lactating mothers. Ciprofloxacin was reported to cause arthralgia and degenerative changes in joints that bear weight in young animals.
