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The recommended dose of apixaban is 5 mg taken orally twice daily.
Method of administration: Oral use.
Apixaban tablets should be swallowed with water, with or without food.
For patients who are unable to swallow whole tablets, Apixaban tablets may be crushed and suspended in water, or 5% dextrose in water (D5W), or apple juice or mixed with apple puree and immediately administered orally. Alternatively, Apixaban tablets may be crushed and suspended in 60 mL of water or D5W and immediately delivered through a nasogastric tube. Crushed Apixaban tablets are stable in water, D5W, apple juice, and apple puree for up to 4 hours.
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