Rosuvastatin is given by mouth in an initial dose of 5 mg to 10 mg in the evening; an initial dose of 20 mg may be used in patients with ischaemic heart disease. The dose may be adjusted at interval of not less than 4 weeks up to maximum of 80 mg once daily in three divided doses of 20 mg, 20 mg and an evening dose of 40 mg. A maximum of 10 mg once daily is recommended in those taking ciclosporine fibric acid derivatives or nicotinic acid, and the risk of myopathy must be considered. Or as prescribed by the physician.
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