The vitamins contained in Vineuron capsule are completely non-toxic even in high dose and usually, no effects occur. Sensitivity to Vitamin B1 however, may sometimes be encountered if administration is at prolonged intervals. Liver dysfunctions could also predispose patients to hypersensitivity reactions. Nevertheless, it must be stressed that hypersensitivity to Vitamin B1 is very rare when orally given unlike if administered by intravenous injection where hypersensitivity is more often encountered.