Viamox Dosage/Direction for Use

Doses are expressed throughout in terms of amoxicillin/clavulanic acid content except when doses are stated in terms of an individual component.
The dose of tablet that is selected to treat an individual infection should take into account: The expected pathogens and their likely susceptibility to antibacterial agents.
The severity and the site of the infection.
The age, weight and renal function of the patient are as follows.
The use of alternative presentations of product (e.g. those that provide higher doses of amoxicillin and/or different ratios of amoxicillin to clavulanic acid) should be considered as necessary.
For adults and children ≥40 kg, this formulation of this tablet provides a total daily dose of 1500 mg amoxicillin/375 mg clavulanic acid, when administered as follows. For children <40 kg, this formulation of product provides a maximum daily dose of 2400 mg amoxicillin/600 mg clavulanic acid, when administered as follows. If it is considered that a higher daily dose of amoxicillin is required, it is recommended that another preparation of Tablet is selected in order to avoid administration of unnecessarily high daily doses of clavulanic acid.
The duration of therapy should be determined by the response of the patient. Some infections (e.g. osteomyelitis) require longer periods of treatment. Treatment should not be extended beyond 14 days without review.
Adults and children ≥40 kg: One 500 mg/125 mg tablet taken three times a day.
Children <40 kg: 20 mg/5 mg/kg/day to 60 mg/15 mg/kg/day given in three divided doses.
Children may be treated with this tablets or suspensions.
As the tablets cannot be divided, children weighing less than 25 kg must not be treated with this tablet.
The table as follows presents the received dose (mg/kg body weight) in children weighing 25 kg to 40 kg upon administering a single 500/125 mg tablet. (See Table 4.)

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Children aged 6 years and below or weighing less than 25 kg should preferably be treated with amoxiclav suspension.
No clinical data are available on doses of tablet 4:1 formulation higher than 40 mg/10 mg/kg per day in children under 2 years.
Elderly: No dose adjustment is considered necessary.
Renal impairment: Dose adjustments are based on the maximum recommended level of amoxicillin.
No adjustment in dose is required in patients with creatinine clearance (CrCl) greater than 30 mL/min.
Adults and children ≥40 kg: See Table 5.

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Children <40 kg: See Table 6.

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Hepatic impairment: Dose with caution and monitor hepatic function at regular intervals.
Method of administration: The tablet is for oral use.
Viamox should be administered with a meal to minimise potential gastrointestinal intolerance.
Therapy can be started parenterally according to the SPC of the IV-formulation and continued with an oral preparation.