Viacoram Initio/Viacoram Dosage/Direction for Use

Posology: Oral use.
Perindopril arginine + Amlodipine besilate (Viacoram Initio) 3.5 mg/2.5 mg is intended for first line therapy in patients with arterial hypertension.
The recommended starting dose is 1 tablet once daily.
After at least four weeks of treatment, the dose may be increased to Perindopril arginine + Amlodipine besilate (Viacoram) 7 mg/5 mg once daily in patients whose blood pressure is not adequately controlled with Viacoram 3.5 mg/2.5 mg dose.
Special populations: Patients with renal impairment: Perindopril arginine + Amlodipine besilate (Viacoram Initio/Viacoram) is contraindicated in patients with severe renal impairment (Creatinine clearance below 30 mL/min).
In patients with moderate renal impairment (Creatinine clearance between 30 mL/min to 60 mL/min), the initial recommended dose is 3.5 mg/2.5 mg every other day.
In patients whose blood pressure is not adequately controlled, the 3.5 mg/2.5 mg dose may be taken once daily. If necessary, the dose may be increased in patients insufficiently controlled.
The usual medical follow-up includes monitoring of creatinine and potassium.
Patients with hepatic impairment: Caution should be exercised when prescribing Perindopril arginine + Amlodipine besilate (Viacoram Initio/Viacoram) to patients with severe hepatic impairment.
Older people: The efficacy and safety of Perindopril arginine + Amlodipine besilate (Viacoram Initio/Viacoram) have been established in older people. Caution should be exercised at initiation depending on renal function.
After initiation of the treatment, renal function should be monitored before increase of the dosage, particularly in patients aged 75 years and above.
The usual medical follow-up should include monitoring of creatinine and potassium.
Pediatric population: The safety and efficacy of Perindopril arginine + Amlodipine besilate (Viacoram Initio/Viacoram) in children aged below 18 years have not been established. No data are available.
Method of administration: The tablet of Perindopril arginine + Amlodipine besilate (Viacoram Initio/Viacoram) should be taken as a single dose, preferably in the morning and before a meal.
Missed Dose: It is important to take the medicine every day as regular treatment works better. However, if a dose is forgotten, take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose.
Discontinuation of Treatment: As the treatment with Perindopril arginine + Amlodipine besilate (Viacoram Initio/Viacoram) is usually life-long, discuss with the doctor before stopping the treatment.
For any further questions on the use of this medicine, ask the doctor or pharmacist.