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Adults: 1 tablet in the morning and evening during meals.
Patients with moderate renal impairment (creatinine clearance 30-60 mL/min) and Elderly patients: 1 tablet in the morning during breakfast.
Or, as prescribed by a physician.
The modified-release tablet should be swallowed whole with a glass of water. Do not chew or crush the modified-release tablet since this may cause inappropriate release and absorption of the drug.
The benefit of the drug should be assessed after three months and the drug discontinued if there is no treatment response.
