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Symptoms of felodipine overdose include peripheral vasodilatation with marked hypotension and bradycardia.
Activated charcoal, induction of vomiting or gastric lavage, if necessary.
Institute symptomatic treatment if severe hypotension occurs. Place the patient in supine position with legs elevated. In case of bradycardia, administer intravenous atropine 0.5 to 1 mg IV. If this is not sufficient, increase plasma volume by infusion of glucose, saline or dextran. Sympathomimetic agents with predominant effect on the α1-adrenoceptor may be given if the previously mentioned measures are insufficient.
It has not been established whether felodipine can be removed by hemodialysis.
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