Pre-exposure prophylaxis Immunocompetent individual Conventional regimen: 0.5 mL IM or 0.1 mL intradermal on day 0, 7, & 21 or 28. 1-week regimen: 0.5 mL IM on day 0 & 7; or 2 doses of 0.1 mL intradermal on day 0 & 7.
Individual w/ decreased immunity Follow the conventional 3-dose regimen.
Post-exposure prophylaxis Adjusted to exposure category, condition of animal, & vaccination status of the patient in accordance w/ official recommendations.
Non-immunised individual & individual w/ decreased immunity IM 0.5 mL on day 0, 3, 7, 14 & 28; or 2 doses of 0.5 mL on day 0, followed by 0.5 mL on day 7 & 21.
Intradermal 2 doses of 0.1 mL in 2 separate sites on day 0, 3, 7 & 28; or 2 doses of 0.1 mL in 2 separate sites on day 0, 3 & 7; or 4 doses of 0.1 mL in 4 separate sites on day 0, 3 & 7.
Already immunised individual 1 dose (0.5 mL IM or 0.1 mL intradermal) on day 0 & 3. Alternatively, 4 intradermal inj of 0.1 mL in 4 separate sites on day 0.
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