Patients receiving indapamide should be monitored for signs and symptoms of fluid or electrolyte imbalance; namely hyponatremia, hypochloraemia and hypokalaemia. Blood urea nitrogen and uric acid should also be assessed during therapy. The signs of electrolyte imbalance are dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscle fatigue, hypotension, oliguria, gastrointestinal disturbances such as nausea and vomiting, tachycardia, and ECG changes.